Синтез нової спіросистеми: 1-окса-7-тіа-4-азаспіро [4,5] декан 7,7-діоксид

Abstract

Dihydro-2H-1λ6-thiopyran-1,1,3(4H)-trione reacted with N-substituted 2-aminoethanols to give derivatives of a new spiro system, 1-oxa-7λ6-thia-4-azaspiro[4.5]decane-7,7-diones. No spirocyclic product was obtained by the reaction with unsubstituted 2-aminoethanol, but the corresponding enamine was formed as in the reactions with other primary amines.