Effect of humic feed additive nature "Humilid" on the level of natural resistance and immunologic reactivity puppies provided it is added to the basic diet

Abstract

The results of the study of dynamic changes in hematological indices and the establishment of sensitization by the body in the body of domestic animals based on the action of the feed supplement of humic nature "Humilid" are presented. It is known that feed additives of humic nature are metabolized and have a polyfunctional effect on the organism of animals, since they possess high adaptogenic properties, maintain immune status and take an active part in the regulation of metabolism. It was found that the most pronounced changes in the use of the biologically active feed supplement of humic nature of Humilid related to the content of total protein and γ-globulin fraction. Thus, in animals of the experimental group, the amount of γ-globulin before the addition of an additive to their diet was on average 9.9 ± 1.45 % of the total protein, and after three weeks, this figure increased to 15.53 ± 1.44 % (difference 5.63%). In the control group at the beginning of the experiment, the number of γ-globulin was 11.3 ± 2.41, and after three weeks - 13.90 ± 0.18 (difference 2.63 %). That is, for the use of the biologically active substance humic nature, an increase in the level of γ-globulin in the blood of animals in the experimental group is on average 3% relative to the control. At the same time, this dynamics is recorded by the indexes of albumin content, λ1-globulins, λ2-globulins, β-globulins. It is established, adding to the basic diet of domestic animals biologically active feed supplement humic nature "Humilid" does not cause sensitization of the organism to the constituent of the active substances of the feed supplement. Inclusion in the main pet's diet Humilid, on the contrary, has a desensitizing effect, as evidenced by a decrease in the number of eosinophils in the blood of experimental animals. The main quantitative changes in the blood cell population, due to the action of the biologically active feed supplement of humic nature Humilid, is associated with the cell line of the innate immunity of the organism, as evidenced by an increase in the total number of granulocytes and monocytes.