Перспективи використання нанопрепарату “Каплаестрол+OV” у ветеринарній репродуктології

Abstract

Визначено ефективність та перспективи використання нанопрепарату “Каплаестрол+OV” у ветеринарній репродуктології. Встановлено, він є ефективним за застосування його у схемах терапевтичних та превентивних заходів за репродуктивних патологій продуктивних тварин, зокрема у способі нормалізації структури і функції фето-плацентарного комплексу та підвищення потенціалу розвитку новонароджених і програмах терапії самок з гонадодистрофією та гіпогонадизмом, а отже може бути рекомендованим для практики ветеринарної медицини. The nanotechnology – one of the key areas of industrial development and progress of society. In veterinary medicine along with traditional chemical medicines for pets are increasingly being used bioactive therapy that complements the chemical treatment and is aimed at use of the body to regulate and drugs of natural origin. The positive results of the application of nanotechnology to encourage further research in veterinary medicine, particularly in the field of animal reproduction. The aim of research was to determine the effectiveness and prospects of nanopreparate “Caplaestrol+OV” in veterinary reproduction. It is known that under the influence of negative factors influence there is an imbalance in the system prooxidant-antioxidant oxidation and cytotoxic hypoxia, resulting in the pathological process at the cellular level. So it is logical to use materials that would impact on the prooxidant- antioxidant system and oxygen metabolism. Given this, in order to improve therapeutic efficacy “Caplaestrol+OV”, containing carotenoids and estrogens, focused on nanobiomaterials, in particular orthovanadate rare earth elements. Established that the use nanopreparat “Caplaestrol+OV” almost all the studied parameters reach values characteristic of animals with physiological constants. In general, a normalization of imbalance prooxidant-antioxidant system, as well as improvements in oxygen metabolism. In particular, in the way of normalization of the structure and function fetoplacental complex and increasing the development potential in the placenta of new-born experimental animals were no degenerative processes, significantly increased litter weight and total villous chorion area and mass concentration of maternal and neonatal immunoglobulins. The program of therapy animals with gonadodystrophy and hypogonadism is the restoration of the structure and function of the gonads, expression estrum and improving fertility and reducing the number of days of infertility. Thus, nanopreparat “Caplaestrol+OV” is effective for its use in therapeutic regimens and preventive measures for reproductive abnormalities farm animals and can be recommended for the practice of veterinary medicine. In the future, will be tested “Caplaestrol+OV” and other nanopreparats for the treatment and prevention of obstetric, gynecological and andrological diseases of small animals.